Thu, 08/26/2021 - 20:58
Science goes fast. To my overview of this morning, this important preprint should be added: Thiago Cerqueira-Silva Effectiveness of Vaxzevria (= Astra-Zeneca) and CoronaVac vaccines in Brazil medRxiv 25 Aug 2021. As you can read, this is a nationwide retrospective comparison on tens of millions. I summarize the main findings in the table.
During the study period (Jan-June), the gamma variant was most prevalent in Brazil
- As expected, both vaccines are active, but clearly Vaxzevria > CoronaVac.
- In elderly over 90 (not at lower ages) both vaccines lose a lot of activity
Since Vaxzevria = Covishield, Ep 165-30 suggest that a heterologous combination may be superior.
18 Feb 2023 Episode 316: Under which circumstances could type I or type III IFN be a useful treatment?
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